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Loss of Hdac3 in osteoprogenitors increases bone expression of osteoprotegerin, improving systemic insulin sensitivity

Type 2 diabetes is an emerging global health epidemic. Foundations for new therapies are arising from understanding interactions between body systems. Bone-derived factors that reduce RANKL (receptor activator of NF-kappa B ligand) signaling in the liver may prevent insulin resistance and the onset...

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Bibliografske podrobnosti
izdano v:J Cell Physiol
Main Authors: McGee-Lawrence, Meghan E., Pierce, Jessica L., Yu, Kanglun, Culpepper, Natasha R., Bradley, Elizabeth W., Westendorf, Jennifer J.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741476/
https://ncbi.nlm.nih.gov/pubmed/28840938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.26148
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