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Fisetin inhibits epidermal growth factor–induced migration of ARPE-19 cells by suppression of AKT activation and Sp1-dependent MMP-9 expression

PURPOSE: Proliferative vitreoretinopathy (PVR) can result in abnormal migration of RPE cells. Fisetin is a naturally occurring compound that has been reported to have antitumor effects, but its effects on epidermal growth factor (EGF)–induced cell migration and the underlying mechanisms remain uncle...

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Detalhes bibliográficos
Publicado no:Mol Vis
Main Authors: Lin, Hung-Yu, Chen, Yong-Syuan, Wang, Kai, Chien, Hsiang-Wen, Hsieh, Yi-Hsien, Yang, Shun-Fa
Formato: Artigo
Idioma:Inglês
Publicado em: Molecular Vision 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741382/
https://ncbi.nlm.nih.gov/pubmed/29296070
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