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Metal-Dependent DNA Recognition and Cell Internalization of Designed, Basic Peptides
[Image: see text] A fragment of the DNA basic region (br) of the GCN4 bZIP transcription factor has been modified to include two His residues at designed i and i+4 positions of its N-terminus. The resulting monomeric peptide (brHis(2)) does not bind to its consensus target DNA site (5′-GTCAT-3′). Ho...
Enregistré dans:
| Publié dans: | J Am Chem Soc |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical
Society
2017
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5741177/ https://ncbi.nlm.nih.gov/pubmed/29056048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b07422 |
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