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Evaluation of amplification refractory mutation system (ARMS) technique for quick and accurate prenatal gene diagnosis of CHM variant in choroideremia

Choroideremia is a rare X-linked recessive inherited disorder that causes chorioretinal dystrophy leading to visual impairment in its early stages which finally causes total blindness in the affected person. It is caused due to mutations in the CHM gene. In this study, we have recruited a pedigree w...

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Detalhes bibliográficos
Publicado no:Appl Clin Genet
Main Authors: Yang, Lisha, Ijaz, Iqra, Cheng, Jingliang, Wei, Chunli, Tan, Xiaojun, Khan, Md Asaduzzaman, Fu, Xiaodong, Fu, Junjiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741072/
https://ncbi.nlm.nih.gov/pubmed/29296092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/TACG.S144383
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