HOMINID: a framework for identifying associations between host genetic variation and microbiome composition

Recent studies have uncovered a strong effect of host genetic variation on the composition of host-associated microbiota. Here, we present HOMINID, a computational approach based on Lasso linear regression, that given host genetic variation and microbiome taxonomic composition data, identifies host...

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Enregistré dans:
Détails bibliographiques
Publié dans:Gigascience
Auteurs principaux: Lynch, Joshua, Tang, Karen, Priya, Sambhawa, Sands, Joanna, Sands, Margaret, Tang, Evan, Mukherjee, Sayan, Knights, Dan, Blekhman, Ran
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Technical Note
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740987/
https://ncbi.nlm.nih.gov/pubmed/29126115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/gix107
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