Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death

BACKGROUND: Lung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant patients. This study investigates the anti-inflammatory and immunomodulatory role of human mesenchymal stromal cells (MSCs) and...

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Foilsithe in:Respir Res
Main Authors: Stone, Matthew L., Zhao, Yunge, Robert Smith, J., Weiss, Mark L., Kron, Irving L., Laubach, Victor E., Sharma, Ashish K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740880/
https://ncbi.nlm.nih.gov/pubmed/29268735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-017-0704-9
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