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AP-4 mediates export of ATG9A from the trans-Golgi network to promote autophagosome formation

AP-4 is a member of the heterotetrameric adaptor protein (AP) complex family involved in protein sorting in the endomembrane system of eukaryotic cells. Interest in AP-4 has recently risen with the discovery that mutations in any of its four subunits cause a form of hereditary spastic paraplegia (HS...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Mattera, Rafael, Park, Sang Yoon, De Pace, Raffaella, Guardia, Carlos M., Bonifacino, Juan S.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740629/
https://ncbi.nlm.nih.gov/pubmed/29180427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1717327114
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