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Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro
Activation of protein C is greatly enhanced by the presence of thrombomodulin (TM) and endothelial protein C receptor (EPCR) on the endothelial surface. Impairment of the anticoagulant protein C system occurs during endotoxemia and contributes to sepsis-associated hypercoagulability. Previous studie...
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| Опубликовано в: : | Exp Ther Med |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5740512/ https://ncbi.nlm.nih.gov/pubmed/29285085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5236 |
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