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Unfractionated heparin protects the protein C system against lipopolysaccharide-induced damage in vivo and in vitro

Activation of protein C is greatly enhanced by the presence of thrombomodulin (TM) and endothelial protein C receptor (EPCR) on the endothelial surface. Impairment of the anticoagulant protein C system occurs during endotoxemia and contributes to sepsis-associated hypercoagulability. Previous studie...

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Bibliografski detalji
Izdano u:Exp Ther Med
Glavni autori: Zhao, Dongmei, Ding, Renyu, Liu, Yina, Yin, Xiaohan, Zhang, Zhidan, Ma, Xiaochun
Format: Artigo
Jezik:Inglês
Izdano: D.A. Spandidos 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740512/
https://ncbi.nlm.nih.gov/pubmed/29285085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5236
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