In Vitro Human Onychopharmacokinetic and Pharmacodynamic Analyses of ME1111, a New Topical Agent for Onychomycosis

ME1111 is a novel antifungal agent currently under clinical development as a topical onychomycosis treatment. A major challenge in the application of topical onychomycotics is penetration and dissemination of antifungal agent into the infected nail plate and bed. In this study, pharmacokinetic/pharm...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Kubota-Ishida, Natsuki, Takei-Masuda, Naomi, Kaneda, Kaori, Nagira, Yu, Chikada, Tsubasa, Nomoto, Masahiro, Tabata, Yuji, Takahata, Sho, Maebashi, Kazunori, Hui, Xiaoying, Maibach, Howard I.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2017
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740379/
https://ncbi.nlm.nih.gov/pubmed/29084749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00779-17
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