Combating Multidrug-Resistant Pathogens with Host-Directed Nonantibiotic Therapeutics

Earlier, we reported that three Food and Drug Administration-approved drugs, trifluoperazine (TFP; an antipsychotic), amoxapine (AXPN; an antidepressant), and doxapram (DXP; a breathing stimulant), identified from an in vitro murine macrophage cytotoxicity screen, provided mice with 40 to 60% protec...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Andersson, Jourdan A., Sha, Jian, Kirtley, Michelle L., Reyes, Emily, Fitts, Eric C., Dann, Sara M., Chopra, Ashok K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740341/
https://ncbi.nlm.nih.gov/pubmed/29109161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01943-17
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