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Pharmacokinetic Modeling of Voriconazole To Develop an Alternative Dosing Regimen in Children

The pharmacokinetic variability of voriconazole (VCZ) in immunocompromised children is high, and adequate exposure, particularly in the first days of therapy, is uncertain. A population pharmacokinetic model was developed to explore VCZ exposure in plasma after alternative dosing regimens. Concentra...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Gastine, Silke, Lehrnbecher, Thomas, Müller, Carsten, Farowski, Fedja, Bader, Peter, Ullmann-Moskovits, Judith, Cornely, Oliver A., Groll, Andreas H., Hempel, Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740334/
https://ncbi.nlm.nih.gov/pubmed/29038273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01194-17
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