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Vitamin D Compounds Are Bactericidal against Streptococcus mutans and Target the Bacitracin-Associated Efflux System

Vitamin D analogs were identified as compounds that induced lysis of planktonic cultures of Streptococcus mutans in a high-throughput screen of FDA-approved drugs. Previous studies have demonstrated that certain derivatives of vitamin D possess lytic activity against other bacteria, though the mecha...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Saputo, S., Faustoferri, R. C., Quivey, R. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740330/
https://ncbi.nlm.nih.gov/pubmed/29061743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01675-17
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