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Severe Infusion-Related Adverse Events and Renal Failure in Patients Receiving High-Dose Intravenous Polymyxin B

The use of very high doses of polymyxin B (PMB) against carbapenem-resistant Gram-negative bacilli has been addressed in in vitro experiments as a strategy to improve bacterial killing and suppress resistance emergence. However, the toxicities of very high doses in patients are unknown. We conducted...

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Bibliografiset tiedot
Julkaisussa:Antimicrob Agents Chemother
Päätekijät: John, Josiane F., Falci, Diego R., Rigatto, Maria Helena, Oliveira, Renata D., Kremer, Thaysa G., Zavascki, Alexandre P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740322/
https://ncbi.nlm.nih.gov/pubmed/29038262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01617-17
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