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GPR35 mediates lodoxamide‐induced migration inhibitory response but not CXCL17‐induced migration stimulatory response in THP‐1 cells; is GPR35 a receptor for CXCL17?

BACKGROUND AND PURPOSE: GPR35 has long been considered an orphan GPCR, because no endogenous ligand of GPR35 has been discovered. CXCL17 (a chemokine) has been reported to be an endogenous ligand of GPR35, and it has even been suggested that it be called CXCR8. However, at present there is no suppor...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Park, Soo‐Jin, Lee, Seung‐Jin, Nam, So‐Yeon, Im, Dong‐Soon
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740256/
https://ncbi.nlm.nih.gov/pubmed/29068046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14082
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