Integration of miRNA and gene expression profiles suggest a role for miRNAs in the pathobiological processes of acute Trypanosoma cruzi infection

Chagas disease, caused by the parasite Trypanosoma cruzi, is endemic in Latin America. Its acute phase is associated with high parasitism, myocarditis and profound myocardial gene expression changes. A chronic phase ensues where 30% develop severe heart lesions. Mouse models of T. cruzi infection ha...

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Publicado no:Sci Rep
Main Authors: Ferreira, Ludmila Rodrigues Pinto, Ferreira, Frederico Moraes, Laugier, Laurie, Cabantous, Sandrine, Navarro, Isabela Cunha, da Silva Cândido, Darlan, Rigaud, Vagner Carvalho, Real, Juliana Monte, Pereira, Glaucia Vilar, Pereira, Isabela Resende, Ruivo, Leonardo, Pandey, Ramendra Pati, Savoia, Marilda, Kalil, Jorge, Lannes-Vieira, Joseli, Nakaya, Helder, Chevillard, Christophe, Cunha-Neto, Edecio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740174/
https://ncbi.nlm.nih.gov/pubmed/29269773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18080-9
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