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Hepatocyte-derived exosomes promote T follicular regulatory cell expansion during HCV infection

Hepatitis C virus (HCV) is a global health concern that can cause severe liver disease such as cirrhosis and hepatocellular carcinoma. Control of HCV requires vigorous T cell responses, yet CD4(+) T cells in chronic HCV patients are dysfunctional. T follicular regulatory (Tfr) cells are a subset of...

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Detalhes bibliográficos
Publicado no:Hepatology
Main Authors: Cobb, Dustin A., Golden-Mason, Lucy, Rosen, Hugo R., Hahn, Young S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739980/
https://ncbi.nlm.nih.gov/pubmed/28749570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29409
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