Targeting Hypersensitive Corticostriatal Terminals in Restless Legs Syndrome

OBJECTIVE: The first aim was to demonstrate a previously hypothesized increased sensitivity of corticostriatal glutamatergic terminals in the rodent with brain iron deficiency (BID), a pathogenetic model of Restless Legs Syndrome (RLS). The second aim was to determine if these putative hypersensitiv...

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Bibliographic Details
Published in:Ann Neurol
Main Authors: Yepes, Gabriel, Guitart, Xavier, Rea, William, Newman, Amy H., Allen, Richard P., Earley, Christopher J., Quiroz, César, Ferré, Sergi
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739944/
https://ncbi.nlm.nih.gov/pubmed/29171915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.25104
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