Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

OBJECTIVE: Neutrophils are prominent components of solid tumours and exhibit distinct phenotypes in different tumour microenvironments. However, the nature, regulation, function and clinical relevance of neutrophils in human gastric cancer (GC) are presently unknown. DESIGN: Flow cytometry analyses...

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Publicado en:Gut
Main Authors: Wang, Ting-ting, Zhao, Yong-liang, Peng, Liu-sheng, Chen, Na, Chen, Weisan, Lv, Yi-pin, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Teng, Yong-sheng, Fu, Xiao-long, Yu, Pei-wu, Guo, Gang, Luo, Ping, Zhuang, Yuan, Zou, Quan-ming
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2017
Assuntos:
Stomach
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739867/
https://ncbi.nlm.nih.gov/pubmed/28274999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313075
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