Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

OBJECTIVE: Neutrophils are prominent components of solid tumours and exhibit distinct phenotypes in different tumour microenvironments. However, the nature, regulation, function and clinical relevance of neutrophils in human gastric cancer (GC) are presently unknown. DESIGN: Flow cytometry analyses...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Wang, Ting-ting, Zhao, Yong-liang, Peng, Liu-sheng, Chen, Na, Chen, Weisan, Lv, Yi-pin, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Teng, Yong-sheng, Fu, Xiao-long, Yu, Pei-wu, Guo, Gang, Luo, Ping, Zhuang, Yuan, Zou, Quan-ming
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Stomach
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739867/
https://ncbi.nlm.nih.gov/pubmed/28274999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313075
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