Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

OBJECTIVE: Neutrophils are prominent components of solid tumours and exhibit distinct phenotypes in different tumour microenvironments. However, the nature, regulation, function and clinical relevance of neutrophils in human gastric cancer (GC) are presently unknown. DESIGN: Flow cytometry analyses...

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Bibliographic Details
Published in:Gut
Main Authors: Wang, Ting-ting, Zhao, Yong-liang, Peng, Liu-sheng, Chen, Na, Chen, Weisan, Lv, Yi-pin, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Teng, Yong-sheng, Fu, Xiao-long, Yu, Pei-wu, Guo, Gang, Luo, Ping, Zhuang, Yuan, Zou, Quan-ming
Format: Artigo
Language:Inglês
Published: BMJ Publishing Group 2017
Subjects:
Stomach
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739867/
https://ncbi.nlm.nih.gov/pubmed/28274999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313075
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