Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

OBJECTIVE: Neutrophils are prominent components of solid tumours and exhibit distinct phenotypes in different tumour microenvironments. However, the nature, regulation, function and clinical relevance of neutrophils in human gastric cancer (GC) are presently unknown. DESIGN: Flow cytometry analyses...

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Udgivet i:Gut
Main Authors: Wang, Ting-ting, Zhao, Yong-liang, Peng, Liu-sheng, Chen, Na, Chen, Weisan, Lv, Yi-pin, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Teng, Yong-sheng, Fu, Xiao-long, Yu, Pei-wu, Guo, Gang, Luo, Ping, Zhuang, Yuan, Zou, Quan-ming
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2017
Fag:
Stomach
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739867/
https://ncbi.nlm.nih.gov/pubmed/28274999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313075
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