Tumour-activated neutrophils in gastric cancer foster immune suppression and disease progression through GM-CSF-PD-L1 pathway

OBJECTIVE: Neutrophils are prominent components of solid tumours and exhibit distinct phenotypes in different tumour microenvironments. However, the nature, regulation, function and clinical relevance of neutrophils in human gastric cancer (GC) are presently unknown. DESIGN: Flow cytometry analyses...

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Dades bibliogràfiques
Publicat a:Gut
Autors principals: Wang, Ting-ting, Zhao, Yong-liang, Peng, Liu-sheng, Chen, Na, Chen, Weisan, Lv, Yi-pin, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Teng, Yong-sheng, Fu, Xiao-long, Yu, Pei-wu, Guo, Gang, Luo, Ping, Zhuang, Yuan, Zou, Quan-ming
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2017
Matèries:
Stomach
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739867/
https://ncbi.nlm.nih.gov/pubmed/28274999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-313075
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