A first-in-human clinical study of a new SP-B and SP-C enriched synthetic surfactant (CHF5633) in preterm babies with respiratory distress syndrome

OBJECTIVE: CHF5633 (Chiesi Farmaceutici S.p.A., Parma, Italy) is the first fully synthetic surfactant enriched by peptide analogues of two human surfactant proteins. We planned to assess safety and tolerability of CHF5633 and explore preliminary efficacy. DESIGN: Multicentre cohort study. PATIENTS:...

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Detalhes bibliográficos
Publicado no:Arch Dis Child Fetal Neonatal Ed
Main Authors: Sweet, David G, Turner, Mark A, Straňák, Zbyněk, Plavka, Richard, Clarke, Paul, Stenson, Ben J, Singer, Dominique, Goelz, Rangmar, Fabbri, Laura, Varoli, Guido, Piccinno, Annalisa, Santoro, Debora, Speer, Christian P
Formato: Artigo
Idioma:Inglês
Publicado em: Archives of Disease in Childhood 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739829/
https://ncbi.nlm.nih.gov/pubmed/28465315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/archdischild-2017-312722
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