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Protease-activated receptor-1 (PAR-1): a promising molecular target for cancer
PAR-1 is expressed not only in epithelium, neurons, astrocytes, immune cells, but also in cancer-associated fibroblasts, ECs (epithelial cells), myocytes of blood vessels, mast cells, and macrophages in tumor microenvironment, whereas PAR-1 stimulates macrophages to synthesize and secrete thrombin a...
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| Published in: | Oncotarget |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Impact Journals LLC
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739818/ https://ncbi.nlm.nih.gov/pubmed/29291033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21015 |
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