Circulating GRP78 antibodies from ovarian cancer patients: a promising tool for cancer cell targeting drug delivery system?

Glucose-regulated protein 78 (GRP78) is a chaperone protein that has a high frequency in tumor cells. Normally it is found in the endoplasmic reticulum to assist in protein folding, but under cellular stress, GRP78 influences proliferative signaling pathways at the cell surface. The increased expres...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Van Hoesen, Kylie, Meynier, Sonia, Ribaux, Pascale, Petignat, Patrick, Delie, Florence, Cohen, Marie
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739806/
https://ncbi.nlm.nih.gov/pubmed/29291021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22412
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