Up-regulation of 5-lipoxygenase by inhibition of cathepsin G enhances TRAIL-induced apoptosis through down-regulation of survivin

Cathepsin G is a serine protease secreted from activated neutrophils, it has important roles in inflammation and immune response. Moreover, cathepsin G promotes tumor cell-cell adhesion and migration in cancer cells. In this study, we investigated whether inhibition of cathepsin G could sensitize TR...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Woo, Seon Min, Min, Kyoung-Jin, Seo, Seung Un, Kim, Shin, Park, Jong-Wook, Song, Dae Kyu, Lee, Hyun-Shik, Kim, Sang Hyun, Kwon, Taeg Kyu
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739765/
https://ncbi.nlm.nih.gov/pubmed/29290980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22508
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