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Neurocan, an extracellular chondroitin sulfate proteoglycan, stimulates neuroblastoma cells to promote malignant phenotypes

Neurocan (NCAN), a secreted chondroitin sulfate proteoglycan, is one of the major inhibitory molecules for axon regeneration in nervous injury. However, its role in cancer is not clear. Here we observed that high NCAN expression was closely associated with the unfavorable outcome of neuroblastoma (N...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Su, Zhendong, Kishida, Satoshi, Tsubota, Shoma, Sakamoto, Kazuma, Cao, Dongliang, Kiyonari, Shinichi, Ohira, Miki, Kamijo, Takehiko, Narita, Atsushi, Xu, Yinyan, Takahashi, Yoshiyuki, Kadomatsu, Kenji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739734/
https://ncbi.nlm.nih.gov/pubmed/29290949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22435
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