Puerarin attenuates locomotor and cognitive deficits as well as hippocampal neuronal injury through the PI3K/Akt1/GSK-3β signaling pathway in an in vivo model of cerebral ischemia

Ischemic stroke causes irreversible damage to the brain. The hippocampus is a vulnerable region and plays an important role in cognition and locomotor activity. Puerarin is a phytoestrogen that has beneficial effects in treating neurological disorders. How puerarin protects against hippocampal injur...

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Опубликовано в: :Oncotarget
Главные авторы: Tao, Jinhao, Cui, Yuehua, Duan, Yu, Zhang, Nan, Wang, Congmin, Zhang, Fayong
Формат: Artigo
Язык:Inglês
Опубликовано: Impact Journals LLC 2017
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739733/
https://ncbi.nlm.nih.gov/pubmed/29290948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22290
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