Bevacizumab-mediated tumor vasculature remodelling improves tumor infiltration and antitumor efficacy of GD2-CAR T cells in a human neuroblastoma preclinical model

GD2-redirected chimeric antigen receptor (CAR) T lymphocytes represent a promising therapeutic option for immunotherapy of neuroblastoma (NB). However, despite the encouraging therapeutic effects observed in some hematological malignancies, clinical results of CAR T cell immunotherapy in solid tumor...

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Vydáno v:Oncoimmunology
Hlavní autoři: Bocca, Paola, Di Carlo, Emma, Caruana, Ignazio, Emionite, Laura, Cilli, Michele, De Angelis, Biagio, Quintarelli, Concetta, Pezzolo, Annalisa, Raffaghello, Lizzia, Morandi, Fabio, Locatelli, Franco, Pistoia, Vito, Prigione, Ignazia
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2017
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739560/
https://ncbi.nlm.nih.gov/pubmed/29296542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1378843
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