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Interplay between alternatively spliced Tissue Factor and full length Tissue Factor in modulating coagulant activity of endothelial cells

BACKGROUND: Full length Tissue factor (flTF) is a key player in hemostasis and also likely contributes to venous thromboembolism (VTE), the third most common cardiovascular disease. flTF and its minimally coagulant isoform, alternatively spliced TF (asTF), have been detected in thrombi, suggesting p...

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Vydáno v:Thromb Res
Hlavní autoři: Ünlü, B., Bogdanov, V.Y., Versteeg, H.H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739307/
https://ncbi.nlm.nih.gov/pubmed/28570958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.thromres.2017.05.028
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