Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren’s syndrome

OBJECTIVES: Multiomics study was conducted to elucidate the crucial molecular mechanisms of primary Sjögren’s syndrome (SS) pathology. METHODS: We generated multiple data set from well-defined patients with SS, which includes whole-blood transcriptomes, serum proteomes and peripheral immunophenotypi...

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Publicado en:Ann Rheum Dis
Autores principales: Tasaki, Shinya, Suzuki, Katsuya, Nishikawa, Ayumi, Kassai, Yoshiaki, Takiguchi, Maiko, Kurisu, Rina, Okuzono, Yuumi, Miyazaki, Takahiro, Takeshita, Masaru, Yoshimoto, Keiko, Yasuoka, Hidekata, Yamaoka, Kunihiro, Ikeura, Kazuhiro, Tsunoda, Kazuyuki, Morita, Rimpei, Yoshimura, Akihiko, Toyoshiba, Hiroyoshi, Takeuchi, Tsutomu
Formato: Artigo
Lenguaje:Inglês
Publicado: Annals of the Rheumatic Diseases 2017
Materias:
Basic and Translational Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738597/
https://ncbi.nlm.nih.gov/pubmed/28522454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210788
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