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Regulation of ribonucleotide synthesis by the Pseudomonas aeruginosa two-component system AlgR in response to oxidative stress

Ribonucleotide reductases (RNR) catalyze the last step of deoxyribonucleotide synthesis, and are therefore essential to DNA-based life. Three forms of RNR exist: classes I, II, and III. While eukaryotic cells use only class Ia RNR, bacteria can harbor any combination of classes, granting them adapta...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Crespo, Anna, Pedraz, Lucas, Van Der Hofstadt, Marc, Gomila, Gabriel, Torrents, Eduard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738425/
https://ncbi.nlm.nih.gov/pubmed/29263410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17917-7
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