Convergent microevolution of Cryptococcus neoformans hypervirulence in the laboratory and the clinic

Reference strains are a key component of laboratory research, providing a common background allowing for comparisons across a community of researchers. However, laboratory passage of these strains has been shown to lead to reduced fitness and the attenuation of virulence in some species. In this stu...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Arras, Samantha D. M., Ormerod, Kate L., Erpf, Paige E., Espinosa, Monica I., Carpenter, Alex C., Blundell, Ross D., Stowasser, Samantha R., Schulz, Benjamin L., Tanurdzic, Milos, Fraser, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738413/
https://ncbi.nlm.nih.gov/pubmed/29263343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18106-2
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