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Cleavage of osmosensitive transcriptional factor NFAT5 by Coxsackieviral protease 2A promotes viral replication

Nuclear factor of activated T cells 5 (NFAT5)/Tonicity enhancer binding protein (TonEBP) is a transcription factor induced by hypertonic stress in the kidney. However, the function of NFAT5 in other organs has rarely been studied, even though it is ubiquitously expressed. Indeed, although NFAT5 was...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Qiu, Ye, Ye, Xin, Zhang, Huifang Mary, Hanson, Paul, Zhao, Guangze, Tong, Lei, Xie, Ronald, Yang, Decheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738146/
https://ncbi.nlm.nih.gov/pubmed/29220410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006744
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