Self-extracellular RNA acts in synergy with exogenous danger signals to promote inflammation

Self-extracellular RNA (eRNA), released from stressed or injured cells upon various pathological situations such as ischemia-reperfusion-injury, has been shown to act as an alarmin by inducing procoagulatory and proinflammatory responses. In particular, M1-polarization of macrophages by eRNA resulte...

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Publicat a:PLoS One
Autors principals: Noll, Frederik, Behnke, Jonas, Leiting, Silke, Troidl, Kerstin, Alves, Gustavo Teixeira, Müller-Redetzky, Holger, Preissner, Klaus T., Fischer, Silvia
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738100/
https://ncbi.nlm.nih.gov/pubmed/29261777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0190002
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