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The Four Hydrophobic Residues on the Hsp70 Inter-Domain Linker Have Two Distinct Roles
The ubiquitous molecular chaperone 70-kDa heat shock proteins (Hsp70) play key roles in maintaining protein homeostasis. Hsp70s contain two functional domains: a nucleotide binding domain and a substrate binding domain. The two domains are connected by a highly conserved inter-domain linker, and all...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5737734/ https://ncbi.nlm.nih.gov/pubmed/21762702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.07.001 |
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