Identification of Plagl1/Zac1 binding sites and target genes establishes its role in the regulation of extracellular matrix genes and the imprinted gene network

PLAGL1/ZAC1 undergoes parental genomic imprinting, is paternally expressed, and is a member of the imprinted gene network (IGN). It encodes a zinc finger transcription factor with anti-proliferative activity and is a candidate tumor suppressor gene on 6q24 whose expression is frequently lost in vari...

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Bibliografische gegevens
Gepubliceerd in:Nucleic Acids Res
Hoofdauteurs: Varrault, Annie, Dantec, Christelle, Le Digarcher, Anne, Chotard, Laëtitia, Bilanges, Benoit, Parrinello, Hugues, Dubois, Emeric, Rialle, Stéphanie, Severac, Dany, Bouschet, Tristan, Journot, Laurent
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2017
Onderwerpen:
Gene regulation, Chromatin and Epigenetics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737700/
https://ncbi.nlm.nih.gov/pubmed/28985358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx672
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