Developmentally regulated higher-order chromatin interactions orchestrate B cell fate commitment

Genome organization in 3D nuclear-space is important for regulation of gene expression. However, the alterations of chromatin architecture that impinge on the B cell-fate choice of multi-potent progenitors are still unclear. By integrating in situ Hi-C analyses with epigenetic landscapes and genome-...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Boya, Ravi, Yadavalli, Anurupa Devi, Nikhat, Sameena, Kurukuti, Sreenivasulu, Palakodeti, Dasaradhi, Pongubala, Jagan M. R.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
Subjects:
Gene regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737614/
https://ncbi.nlm.nih.gov/pubmed/28977418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx722
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