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A G-quadruplex motif in an envelope gene promoter regulates transcription and virion secretion in HBV genotype B

HBV genotypes differ in pathogenicity. In addition, genotype-specific differences in the regulation of transcription and virus replication exist in HBV, but the underlying mechanisms are unknown. Here, we show the presence of a G-quadruplex motif in the promoter of the preS2/S gene; this G-quadruple...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Biswas, Banhi, Kandpal, Manish, Vivekanandan, Perumal
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737607/
https://ncbi.nlm.nih.gov/pubmed/28981800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx823
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