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Genome-scale detection of positive selection in nine primates predicts human-virus evolutionary conflicts

Hotspots of rapid genome evolution hold clues about human adaptation. We present a comparative analysis of nine whole-genome sequenced primates to identify high-confidence targets of positive selection. We find strong statistical evidence for positive selection in 331 protein-coding genes (3%), pinp...

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Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: van der Lee, Robin, Wiel, Laurens, van Dam, Teunis J.P., Huynen, Martijn A.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737536/
https://ncbi.nlm.nih.gov/pubmed/28977405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx704
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