Proteomic identification of histone post-translational modifications and proteins enriched at a DNA double-strand break

Here, we use ChAP-MS (chromatin affinity purification with mass spectrometry), for the affinity purification of a sequence-specific single-copy endogenous chromosomal locus containing a DNA double-strand break (DSB). We found multiple new histone post-translational modifications enriched on chromati...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Wang, Pingping, Byrum, Stephanie, Fowler, Faith C., Pal, Sangita, Tackett, Alan J., Tyler, Jessica K.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
Assuntos:
NAR Breakthrough Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737490/
https://ncbi.nlm.nih.gov/pubmed/29036368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx844
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