DNA residence time is a regulatory factor of transcription repression

Transcription comprises a highly regulated sequence of intrinsically stochastic processes, resulting in bursts of transcription intermitted by quiescence. In transcription activation or repression, a transcription factor binds dynamically to DNA, with a residence time unique to each factor. Whether...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Clauß, Karen, Popp, Achim P., Schulze, Lena, Hettich, Johannes, Reisser, Matthias, Escoter Torres, Laura, Uhlenhaut, N. Henriette, Gebhardt, J. Christof M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Gene regulation, Chromatin and Epigenetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737411/
https://ncbi.nlm.nih.gov/pubmed/28977492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx728
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