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Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells

Direct reprogramming can be achieved by forced expression of master transcription factors. Yet how such factors mediate repression of initial cell-type-specific genes while activating target cell-type-specific genes is unclear. Through embryonic stem (ES) to trophoblast stem (TS)-like cell reprogram...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Rhee, Catherine, Lee, Bum-Kyu, Beck, Samuel, LeBlanc, Lucy, Tucker, Haley O., Kim, Jonghwan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737334/
https://ncbi.nlm.nih.gov/pubmed/28973471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx692
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