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Initiating ribosomes and a 5′/3′-UTR interaction control ribonuclease action to tightly couple B. subtilis hbs mRNA stability with translation

We previously showed that ribosomes initiating translation of the B. subtilis hbs mRNA at a strong Shine–Dalgarno sequence block the 5′ exoribonuclease RNase J1 from degrading into the coding sequence. Here, we identify new and previously unsuspected features of this mRNA. First, we identify RNase Y...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Braun, Frédérique, Durand, Sylvain, Condon, Ciarán
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737220/
https://ncbi.nlm.nih.gov/pubmed/28977557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx793
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