Mutational analysis of disease relapse in patients allografted for acute myeloid leukemia

Disease relapse is the major cause of treatment failure after allogeneic stem cell transplantation (allo-SCT) in acute myeloid leukemia (AML). To identify AML-associated genes prognostic of AML relapse post–allo-SCT, we resequenced 35 genes in 113 adults at diagnosis, 49 of whom relapsed. Two hundre...

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Publicado en:Blood Adv
Main Authors: Quek, Lynn, Ferguson, Paul, Metzner, Marlen, Ahmed, Ikhlaaq, Kennedy, Alison, Garnett, Catherine, Jeffries, Sally, Walter, Claudia, Piechocki, Kim, Timbs, Adele, Danby, Robert, Raghavan, Manoj, Peniket, Andrew, Griffiths, Mike, Bacon, Andrew, Ward, Janice, Wheatley, Keith, Vyas, Paresh, Craddock, Charles
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Transplantation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737177/
https://ncbi.nlm.nih.gov/pubmed/29296935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016000760
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