Targeted deep sequencing in primary myelofibrosis

A myeloid neoplasm–relevant 27-gene panel was used for next-generation sequencing of bone marrow or whole blood DNA in 182 patients with primary myelofibrosis (PMF). DNA sequence variants/mutations other than JAK2/CALR/MPL were detected in 147 patients (81%), with the most frequent being ASXL1 (36%)...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Tefferi, Ayalew, Lasho, Terra L., Finke, Christy M., Elala, Yoseph, Hanson, Curtis A., Ketterling, Rhett P., Gangat, Naseema, Pardanani, Animesh
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2016
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737166/
https://ncbi.nlm.nih.gov/pubmed/29296803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2016000208
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