Immune tolerance induction by nonmyeloablative haploidentical HSCT combining T-cell depletion and posttransplant cyclophosphamide

The establishment of safe approaches to attain durable donor-type chimerism and immune tolerance toward donor antigens represents a major challenge in transplantation biology. Haploidentical hematopoietic stem cell transplantation (HSCT) is currently used for cancer therapy either as a T-cell–deplet...

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Veröffentlicht in:Blood Adv
Hauptverfasser: Aversa, Franco, Bachar-Lustig, Esther, Or-Geva, Noga, Prezioso, Lucia, Bonomini, Sabrina, Manfra, Ilenia, Monti, Alessandro, Schifano, Chiara, Zlotnikov-Klionsky, Yael, Martelli, Massimo F., Sammarelli, Gabriella, Sassi, Maria, Soli, Maurizio, Giuliodori, Silvia, Benecchi, Magda, Giuliani, Nicola, Lohr, Frank, Pratissoli, Silvia, Reisner, Yair
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2017
Schlagworte:
Transplantation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737124/
https://ncbi.nlm.nih.gov/pubmed/29296864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2017009423
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