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Unravelling the specificity and mechanism of sialic acid recognition by the gut symbiont Ruminococcus gnavus
Ruminococcus gnavus is a human gut symbiont wherein the ability to degrade mucins is mediated by an intramolecular trans-sialidase (RgNanH). RgNanH comprises a GH33 catalytic domain and a sialic acid-binding carbohydrate-binding module (CBM40). Here we used glycan arrays, STD NMR, X-ray crystallogra...
Tallennettuna:
| Julkaisussa: | Nat Commun |
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| Päätekijät: | , , , , , , , , , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Nature Publishing Group UK
2017
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5736709/ https://ncbi.nlm.nih.gov/pubmed/29259165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02109-8 |
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