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Beneficial mutation-selection dynamics in finite asexual populations: a free boundary approach

Using a free boundary approach based on an analogy with ice melting models, we propose a deterministic PDE framework to describe the dynamics of fitness distributions in the presence of beneficial mutations with non-epistatic effects on fitness. Contrarily to most approaches based on deterministic m...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Roques, Lionel, Garnier, Jimmy, Martin, Guillaume
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736637/
https://ncbi.nlm.nih.gov/pubmed/29259180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17212-5
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