Whole exome sequencing identified sixty-five coding mutations in four neuroblastoma tumors

Neuroblastoma is a pediatric tumor characterized by histologic heterogeneity, and accounts for ~15% of childhood deaths from cancer. The five-year survival for patients with high-risk stage 4 disease has not improved in two decades. We used whole exome sequencing (WES) to identify mutations present...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Miller, Aubrey L., Garcia, Patrick L., Pressey, Joseph G., Beierle, Elizabeth A., Kelly, David R., Crossman, David K., Council, Leona N., Daniel, Richard, Watts, Raymond G., Cramer, Stuart L., Yoon, Karina J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736554/
https://ncbi.nlm.nih.gov/pubmed/29259192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17162-y
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